Melanoma, a highly aggressive type of skin cancer originating from pigment-producing cells called melanocytes, can be a source of diagnostic confusion for pathologists. While primary
High-grade serous ovarian cancer (HGSC) is known to have a high degree of both genetic and immunologic heterogeneity, can be resistant to chemotherapy, and commonly
SARS-CoV-2 vaccines based on the ancestral Wuhan-Hu-1 Spike (S) protein have been shown to be effective in preventing severe COVID-19, hospitalization, and death. The evolution
SARS-CoV-2, the causative agent of COVID-19, has been the focus of intense research since its detection in late 2019. It is known that viral infection
Schwannomas are sporadic, usually benign tumors that develop predominately on spinal nerve roots and cranial nerves. Inactivation of NF2 in Schwann cells (SC) is the
Cellular mechanisms of heterogeneity in NF2-mutant schwannoma Read More »
Stereotactic body radiotherapy (SBRT) uses multiple targeted beams of radiation to damage malignant cells while limiting effects to surrounding tissue. SBRT is a standard treatment
This study examined CD8+ cell distribution in hepatocellular carcinoma (HCC) and peritumoral liver tissue to investigate the overall survival (OS) and recurrence-free survival (RFS). It
EZH2 is the catalytic component of Polycomb Repressive Complex 2 (PRC2) and performs trimethylation of histone H3 at lysine 27 (H3K27me3) to silence chromatin. PRC2
Kusmartseva, I., Wu, W., Syed, F. et al. ACE2 and SARS-CoV-2 Expression in the Normal and COVID-19 Pancreas. This article is a preprint and has
ACE2 and SARS-CoV-2 Expression in the Normal and COVID-19 Pancreas Read More »
Predictive biomarkers to determine which non small cell lung cancer (NSCLC) patients will respond to immunotherapy are currently lacking. In this Nature Cancer publication, the
