Indica
Backed by cutting edge technology, an uncompromising focus on ease-of-use and dedicated customer service, Indica Labs’ software and services are being used to make vital discoveries in pathology labs and research organizations around the world.
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Axon Quantification

AXON

Product Overview

The Axon module counts and measures axons and myelin areas in nerve cross-sections. Since axon cross-sections are irregularly shaped, the algorithm uses image processing techniques to detect each axon’s minimum and median diameter. Once each axon has been measured the software generates important statistics including the average inner and outer diameters, average G-Ratio, average perimeter, total axon area, total myelin area, and average myelin thickness. Additionally, it produces several histograms including an axon G-Ratio histogram.

In the example shown above, the inside of each axon (the non-myelin positive area) is highlighted red and the outside boundary of each axon is demarcated with a yellow outline.

The Axon Quantification module integrates seamlessly into the HALO™ platform which is compatible with a number of third party systems and  file formats.

Contact info@indicalab.com for product demonstration and pricing information or upload some images for a free trial.

AXON

The Axon module counts and measures axons and myelin areas in nerve cross-sections. Since axon cross-sections are irregularly shaped, the algorithm uses image processing techniques to detect each axon’s minimum and median diameter. Once each axon has been measured the software generates important statistics including the average inner and outer diameters, average G-Ratio, average perimeter, total axon area, total myelin area, and average myelin thickness. Additionally, it produces several histograms including an axon G-Ratio histogram.

In the example shown above, the inside of each axon (the non-myelin positive area) is highlighted red and the outside boundary of each axon is demarcated with a yellow outline.

HALO is compatible with a broad spectrum of image and digital slide formats.  Yours not on the list? Email us your requirements.

Non-proprietary (JPG, TIF)
Nikon (ND2)
3D Histech (MRXS)
Perkin Elmer (QPTIFF, component TIFF)
Olympus (VSI)
Hamamatsu (NDPI, NDPIS)
Aperio (SVS, AFI)
Zeiss (CZI)
Leica (SCN, LIF)
Philips (Requires Philips IMS)

Here are a few publications that cite use of the Axon module.  Your publication not on the list?  Drop us an email to let us know about it!

Title Author Year Journal
Intrathecal Administration of AAV/GALC Vectors in 10- 11-Day-Old Twitcher Mice Improves Survival and Is Enhanced by Bone Marrow Transplant Karmuthil-Melethil S, Marshall MS, Heindel C, Jakubauskas B, Bongarzone ER, Gray SJ 2016 Journal of Neuroscience Research

Use the form below to upload up to three images for us to analyze using HALO.  If the form does not display, please click here.