The Membrane IHC module measures membranous immunohistochemical markers on a cell-by-cell basis. This module is color configurable, so it can be used with non-traditional chromogens as well as with DAB. The software reports overall scores and positivity percentages for the entire analysis region (including H-Score) and can be configured to report individual expression profiles for each cell.
In the example above, the software measures Her2 expression in breast tissue. Nuclei and membranes are identified and matched for each cell. Cells are then classified as negative, weak, moderate, or strong positive. Positive cell membranes are color coded yellow, orange, and red, dependent on their degree of positivity.